Multiple Choice Questions (MCQs)
RNA duplexes are ________ stable than DNA duplexes.
These ________ bonds, plus the van der Waals and hydrophobic interactions between the adjacent stacked bases, stabilize the structure of the double helix.
The DNA wrapped around the nucleosome core is continuous and joins one nucleosome core to the next -the linker DNA this 50 bp DNA is complexed with the fifth type of histone. ________
Chromatin is composed of
The Tm of DNA is influenced by
Z-DNA have a
S-adenosylmethionine is a ________ group donor.
Separation of the two strands of the double helix when ________ bonds between the paired bases are disrupted.
When linked to vitamins nucleotides are structural components of several essential coenzymes, for example,
A DNA segment contains 100 Adenine and 100 cytosines, how many nucleotides are present in the segment?
Nucleic acids are a polymer of nucleotide monomeric units. Each nucleotide consists of
The "energy carrier" ATP is an example of a(n):
Which of the following is a palindromic sequence?
The ________ strand is called Template strand while
Purine base found in RNA is
The sugar molecule present in nucleotide is
Find the correct statement about phosphodiester linkage between adjacent nucleotides in nucleic acids
Eukaryotic DNA is associated with tightly bound basic ________, called histones.
Nucleoside contains
Nucleosomes can be packed more tightly to form a polynucleosome also called a nucleofilament or a ________nm fiber.
The difference between thymine and uracil is:
DNA model was presented by Watson and Crick in ________.
The DNA oligonucleotide abbreviated pATCGAC:
A short length of DNA molecule has 80 thymine and 80 guanine bases. The total number of nucleotide in the DNA fragment is
According to Chargaff's Rules which one is not correct
Any regular, stable structure taken up by some or all of the nucleotides in a nucleic acid can be referred to as
There are ________ classes of histones
Which one of the following is true of the pentoses found in nucleic acids?
Certain anticancer drugs, exert their cytotoxic effect by intercalating into the ________ groove of the DNA double helix, thus interfering with RNA and DNA synthesis
Around structural core of the nucleosome, a segment of the DNA double helix is wound nearly twice-approximately ________.
When DNA is heated, the temperature at which ________ of the helical structure is lost is defined as the melting temperature.
A phosphodiester bond is present in
histones are ________ charged
Nucleotides are composed of
Compounds that generate nitrous acid (such as nitrites, nitrates, and nitrosamines) change DNA molecules by:
In living cells, nucleotides and their derivatives can serve as:
single-stranded DNA has a ________ relative absorbance at 260nm wavelength than does double-stranded DNA.
Which one is example of coenzymes
higher GC base pairs increases Tm, because, with three hydrogen bonds, require ________ heat energy to dissociate than AT base pairs.
Nucleotides also serve as carriers of activated intermediates in the synthesis of ________.
DNA replication is
In a double-stranded nucleic acid, cytosine typically base-pairs with:
ATP is a
DNA that is not copied during the synthesis of mRNA is also called as
The phosphodiester bonds that link adjacent nucleotides in both RNA and DNA:
Under appropriate conditions DNA will form a hybrid with a complementary ________.
Disruption of DNA can occur in the laboratory with alteration in
The complex folding of large chromosomes within eukaryotic chromatin and bacterial nucleoids is generally considered ________.
Adenosine 3'-phosphate-5'-phosphosulfate is the ________ donor.
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