In the name of ALLAH, the most beneficient, the most merciful

Bioinformatics II (BIF501)

Multiple Choice Questions (MCQs)

Objective Questions

  1. Protein core is ________.

    1. Hydrophobic
    2. Hydrophilic
    3. Amphipathic
    4. Non-Amphipathic
  2. All human share ________ percentage of their DNA sequence.

    1. 50.8
    2. 70.3
    3. 85.9
    4. 99.9
  3. A forensic scientist will need at least ________ pieces of DNA to be compared.

    1. Two
    2. Three
    3. Four
    4. Five
  4. If you want to create a fingerprint, you might look at ________ different STRs at different places to create a profile.

    1. 10
    2. 20
    3. 30
    4. 40
  5. An association rule has ________ parts.

    1. Two
    2. Three
    3. Four
    4. Five
  6. Which tool is used for threading ________.

    1. Modeller
    2. LOMETS
    3. ECEPPAK
    4. iTasser
  7. CAT is repeated continuously ________ times in a row.

    1. 12 to 14
    2. 15 to 17
    3. 18 to 20
    4. 21 to 23
  8. ________ replicate a small amount of DNA to create a larger sample for analysis.

    1. Polymerase chain Reaction (PCR)
    2. Gel Electrophoresis
    3. Flow cytometry
    4. Mass Spectrometry
  9. In PCR the DNA sample is heated to ________ separate the thread.

    1. 90 degrees
    2. 91 degrees
    3. 92 degrees
    4. 93 degrees
  10. How genes affect persons response to drug is study in ________.

    1. Drug discovery
    2. Pharmacogenetics
    3. Pharmacogenomics
    4. Pharmacophore modeling
  11. How many reads are required to map at 1 RPKM with a transcript of 2Kb length from a total of 40 Million Mapped reads?

    1. 60
    2. 70
    3. 80
    4. 90
  12. In homology modeling fewer than ________ of the predicted first hits are true remoted homologues.

    1. 10%
    2. 20%
    3. 30%
    4. 40%
  13. ________ is encrypted sets of numbers that reflect a person's DNA makeup.

    1. DNA fingerprints
    2. DNA profile
    3. cDNA
    4. DNA sequence reads
  14. ________ is a process of organizing objects into groups whose members are similar in some way.

    1. Classification
    2. Clustering
    3. Grouping
    4. Stacking
  15. Lysis Solution removes the ________ proteins from the DNA.

    1. Polymerase
    2. Histone
    3. Helicase
    4. Nuclease
  16. What is meant by ADME in pharmacokinetics?

    1. Affinity, dosage, marketing, efficacy
    2. Absorption, distribution, metabolism, excretion
    3. Agonism, dependence, mobility, efficiency
    4. Antagonism, deficiency, mean, efflux
  17. ________ breaks cell membrane and nuclear envelope causing cells to burst open and release DNA.

    1. Lysis Solution
    2. Nuclease
    3. Protease
    4. Restriction enzymes
  18. In 3D-1D Bowie Algorithm there are ________ distinct states (1D profiles) for 20 amino acid.

    1. 120
    2. 240
    3. 360
    4. 480
  19. Mass spectrometry is used to sequence ________ length proteins.

    1. Smaller
    2. Larger
    3. Medium
    4. All of the given
  20. Neural network is an interconnectrd web of ________.

    1. Networks
    2. Neuron
    3. Nodes
    4. Edges
  21. The length of DNA in a cell is ________.

    1. One meter
    2. Two meters
    3. Three meters
    4. Four meters
  22. iTasser input is ________.

    1. Sequence of DNA
    2. Sequence of RNA
    3. Sequence of Amino Acid
    4. Genome Sequence
  23. Machine learning is used when

    1. Human expertise exists
    2. Humans can explain their expertise like speech recognition
    3. Problem solution changes in time
    4. Problem solution is fixed
  24. Polymerase Chain Reaction is a

    1. DNA degradation technique
    2. DNA amplification technique
    3. DNA sequencing technique
    4. DNA sampling technique
  25. How much percentage of DNA sequence is unique enough to differentiate two humans.

    1. 0.001
    2. 0.01
    3. 0.1
    4. 1.0